James is an Associate Professor in Applied Mathematics at the School of Mathematics and Statistics at the University of Melbourne. His work is at the interface between applied mathematics, scientific computing and biology: he uses mathematical and scientific computing techniques to develop reliable, robust and efficient simulations of multiscale biological and physiological phenomena. James has published over 40 peer reviewed papers, with half as first or senior author. His publications are in both theoretical and applied journals and are usually highly collaborative in nature. Since 2008 he has had a lead role in the development of the multicellular modelling framework Chaste, involving several highly successful international cross-disciplinary collaborations.